| Customization: | Available |
|---|---|
| Product Name: | Indomethacin Suppository |
| Package: | Custom |
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| Product name | Indomethacin suppository |
| Main Ingredients | Indometacin |
| Adaptation disease | This product is anti-inflammatory, and has analgesic, antipyretic effect, used for rheumatoid arthritis, rheumatoid arthritis, tumor pain and tumor blood disease antipyretic |
| Dosage form | Suppository |
| Character | This product is white or light yellow plug made of fatty matrix. |
| Specification | 100mg |
| Usage and dosage | Anal administration, the first plug along the edge of aluminum foil incision tear off a grain, and then along the top of the two layers of aluminum foil tear off the bolt grain, remove the bolt grain, inserted into the anus. One tablet at a time, into the anus, once a day or as directed by a doctor. |
| Storage | Shaded, sealed, stored below 25ºC |
| Origin | China |
| Validity | 48 months |
| Tatoo | 1. Allergic to this product and other antipyretic and analgesic drugs, hemangiedema or bronchospasm should not be used. 2. Contraindicated for the treatment of perioperative pain during coronary artery bypass surgery (CABG). 3. Patients with a history of gastrointestinal bleeding or perforation after using NSAIDS are contraindicated. 4. Patients with active gastrointestinal ulcer/bleeding or a history of recurrent ulcer/bleeding are contraindicated. 5. Contraindicated in patients with severe heart failure. 6. Patients who develop asthma, urticaria or anaphylaxis after taking aspirin or other NSaids should not. 7. This product is metabolized by the liver and excreted by the kidney. It has certain toxicity to the liver and kidney. Therefore, when liver and renal insufficiency, it should be used with caution or forbidden. 8. For patients with epilepsy, Parkinson's disease and mental illness, this product can aggravate the condition and should be used with caution. 9. Patients with hemophilia and other hemorrhagic diseases should use with caution because this product can prolong bleeding time and aggravate bleeding tendency. In addition, this product has an inhibitory effect on the hematopoietic system, and patients with aplastic anemia and granulocytopenia should also be used with caution. |
| Notice | 1. Avoid combination with other nsaids, including selective COX-2 inhibitors. 2. Adverse effects can be minimized by using the lowest effective dose for the shortest treatment time, depending on the need to control symptoms. 3. At any time during treatment with all NSaids, gastrointestinal bleeding, ulcers, and perforation can occur, and the risk can be fatal. These adverse events may or may not be accompanied by warning symptoms, regardless of whether the patient has a history of gastrointestinal adverse events or a history of serious gastrointestinal events. Patients with a prior history of gastrointestinal tract disease (ulcerative colitis, Crohn's disease) should use NSaids with caution to avoid exacerbating the disease. Patients should stop taking the drug when they develop gastrointestinal bleeding or ulcers. Older patients with NSaids experience an increased frequency of adverse reactions, particularly gastrointestinal bleeding and perforation, which can be fatal. 4. Clinical trials of multiple COX-2 selective and non-selective NSAIDs lasting up to 3 years have shown an increased risk of serious cardiovascular thrombotic adverse events, myocardial infarction, and stroke, which may be fatal. All NSAIDs, including COX-2 selective and non-selective drugs, may have similar risks. Patients with CVD or CVD risk factors are at greater risk. Even if there are no previous cardiovascular symptoms, physicians and patients should be vigilant about the occurrence of these events. Patients should be informed of symptoms and/or signs of serious cardiovascular safety and steps to take if they occur. Patients should be alert for signs and symptoms such as chest pain, shortness of breath, weakness, slurred speech, and seek medical help as soon as any of these symptoms or signs occur. 5. Like all non-steroidal anti-inflammatory drugs (NSAIDs), this product can cause new onset of hypertension or worsen existing hypertension, either of which can lead to an increased rate of cardiovascular events. Non-steroidal anti-inflammatory drugs (NSAlDs) may affect the efficacy of these drugs in patients taking thiazide or ansa diuretics. Non-steroidal anti-inflammatory drugs (NSAIDs), including this product, should be used with caution in patients with hypertension. Blood pressure should be closely monitored at the beginning and throughout treatment. 6. Use with caution in patients with a history of hypertension and/or heart failure, such as fluid retention and edema. 7. NSAIDs, including this product, may cause fatal and serious skin adverse reactions, such as exudative dermatitis, Stevens Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN). These serious events can occur without warning. Patients should be informed of the signs and symptoms of severe skin reactions and should be discontinued at the first appearance of a skin rash or other signs of an allergic reaction. 8. Interference to diagnosis: this product can cause transient elevation of serum transaminase, decrease of serum uric acid content, and increase of uric acid content. 9. Regular follow-up examinations should be conducted during the medication period: 1) blood image and liver and kidney function; 2) Regular eye examinations should be conducted for long-term users, as this product can cause corneal deposition and retinal changes (including macular degeneration). An eye examination should be done immediately in case of blurred vision. 10. This product can cause fetal arterioductal atresia and cause persistent pulmonary hypertension in the last 3 months of pregnancy. Pregnant women are not allowed. 11. This product can be discharged from milk, and may cause toxic side effects to infants. Contraindicated for breastfeeding women. 12. Children should use with caution or as advised by doctors. 13. Elderly patients are prone to toxic reactions and should be used with caution. |
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