| Transport Package: | Carton |
|---|---|
| Specification: | 2ml |
| Trademark: | Focus |
| Origin: | China |
| Customization: |
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| Product name | Kanamycin sulfate injection |
| Main Ingredients | Kanamycin sulfate |
| Adaptation disease | This product is used to treat severe infections caused by sensitive bacteria in the family of enterobacteria including Escherichia coli, Klebsiella, Proteus, Enterobacter aeriformis and Shigella wilsonii, such as pneumonia, septicemia and abdominal infection. The latter two bacteria need to be combined with other antibiotics. |
| Dosage form | liquid |
| Character | This product is a clear liquid with colorless to yellowish or yellowish green. |
| Specification | 2ml:0.5g |
| Usage and dosage | 1. For adults, the usual dosage is intramuscular injection or intravenous infusion, 0.5g at a time, once every 12 hours; Or 7.5mg/kg per body weight, every 12 hours, the daily dosage for adults should not exceed 15g, the course of treatment should not exceed 14 days. Doses should be appropriately reduced in patients over 50 years of age. 2, children often use intramuscular injection or intravenous infusion, 15-25mg/kg per day according to body weight, divided into 2 times. 3, renal function decline dosage: creatinine clearance rate of 50-90mg/ min with 60-90% of the normal dose, once every 12 hours (the normal dose is 7.5mg/kg each time, once every 12 hours); Creatinine clearance rate of 10-50mL/min was 30-70% of the normal dose, l times every 12-18 hours; Creatinine clearance <10mg/ min 20-30% of the normal dose, once every 24-48 hours. |
| Storage | seal preservation |
| Origin | China |
| Validity | 24 months |
| Tatoo | 1. Hearing loss, tinnitus or fullness of the ear may occur during the course of treatment, which affects the cochlear nerve. A small number of patients, especially those who previously had renal dysfunction, may occur after drug withdrawal and should be paid attention to. Affect vestibular nerve function can appear vertigo, walking instability, but not much. 2, there may be hematuria, reduced times of urination or decreased urine volume, loss of appetite, nausea, vomiting, extreme thirst and other renal toxic reactions. 3, occasionally dyspnea, lethargy or weakness and other neuromuscular block phenomenon. 4. Other adverse reactions include headache, rash, drug fever, numbness around the mouth, leukopenia, eosinophil hyperplasia, local pain after intramuscular injection, etc. 5. People who have a history of allergy to this product or other aminoglycoside drugs are prohibited. |
| Notice | 1. This product has the potential to cause ototoxicity and nephrotoxicity, so it is not suitable for long-term treatment (such as tuberculosis), usually the boil duration is not more than 14 days. 2. This product should be used with caution in the following cases: patients with water loss, 8th pair cerebral nerve injury, myasthenia gravis or Parkinson's disease, and renal impairment. 3. Patients who are allergic to an aminoglycoside antibiotic, such as streptomycin, gentamicin, or amikacin, may also be allergic to this product. 4. Attention should be paid to the following checks during the medication: (1) Routine urine examination and renal function measurement to prevent severe renal toxicity. (2) Hearing examination or audiogram, especially high frequency audiometry, is more important for the elderly. 5. Blood drug concentration should be monitored when conditions are available, especially in neonates, the elderly and patients with renal dysfunction. The peak concentration should be 15-30μg/ mL and the trough concentration should be 5-10μg/ mL when given once every 12 hours. The peak concentration should be maintained at 56-64μg/ mL and the trough concentration < L μg/ mL when administered once every 24 hours. 6. Interference to diagnosis: it can increase the measured values of alanine aminotransferase (ALT), aspartate aminotransferase (AST), serum bilirubin concentration and serum lactate dehydrogenase concentration; Blood calcium, magnesium, potassium, and sodium concentrations may be decreased. |
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